Created by HELENE MOULIN on Jul 18, 2017 4:59:57 PM, Last modified by HELENE MOULIN on Jul 18, 2017 5:14:35 PM
A 65-year old man presented
with generalized abdominal pain and diarrhea. Several large perianal skin tags
were observed on physical examination, and abdominal imaging revealed irregular
mural thickening of the sigmoid colon. He was treated with corticosteroids for
presumed Crohn colitis, but showed no response and was referred to another
institution. Colonoscopy revealed severe segmental colitis with friable
ulcerated mucosa in the rectosigmoid colon and normal mucosa above 40 cm.
Luminal narrowing precluded examination of the proximal colon. Biopsy samples
were obtained from the sigmoid colon.